PERINATAL OUTCOMES AND PROGNOSTIC FACTORS IN EARLY AND LATE-ONSET FETAL GROWTH RESTRICTION

Objective: To evaluate the obstetric and perinatal outcomes of fetuses with early (EO) late-onset (LO) fetal growth restriction (FGR), to explore prognostic factors on survival adverse outcome. Materials Methods: We retrospectively reviewed 105 EO 55 LO-FGR singleton pregnancies. Umbilical artery (UA), middle cerebral (MCA) ductus venosus (DV) Doppler parameters cerebroplacental ratio (CPR) were assessed. Prognostic significance gestational age at delivery, birth weight evaluated. Results: Gestational delivery greater than 27 weeks (sensitivity 87.5%, specificity 76%) 665 g 88.8%, 92%) provided best prediction in EO-FGR. Logistic regression analysis UA absent or reversed end diastolic flow (EDF), abnormal DV Doppler, absent/reversed a-wave revealed Odds Ratios 2.57, 6.97, 4.51 8.75 respectively for mortality The incidence CPR below 5th percentile was significantly higher pregnancies composite outcome normal (p<0.001). Conclusion: are strongest predictors In LOFGR, <5th is associated an increased risk complications.